DECABOLIN – Nandrolone Decanoate 250mg/ml 5x2ml Box
PHARMACEUTICAL NAME: Nandrolone Decanoate
MOLECULAR STRUCTURE: C28H44O3
PROPRIETARY NAME: DECABOLIN
DOSAGE FORM: 250 mg/ml injection
COMPOSITION: Each ml of DECABOLIN contains Nandrolone Decanoate 250 mg in oily base quantity sufficient.
PHARMACOLOGICAL CLASSIFICATION: Anabolic Steroids
DESCRIPTION:
DECABOLIN is having both androgenic and anabolic properties when administered parentally. Nandrolone decanoate is gradually released from the intramuscular depot and subsequently hydrolyzed into Nandrolone.
INDICATIONS:
1) Anabolic steroid.
2) DECABOLIN is indicated in the treatment of anemia associated with renal insufficiency.
3) Certain cases of disseminated breast cancer in post-menopausal women and women without ovaries.
4) Osteoporosis due to androgen deficiency in hypogonadal males.
CONTRAINDICATIONS:
Contraindicated in infant, pregnancy & lactating mothers. Carcinoma of prostate and carcinoma of male breast. It is not intended for use in female patients other than those with disseminated breast cancer. Contraindicated in nephrosis or the nephrotic phase of nephritis, cardiac and renal failure, hypercalcaemia, oedema, jaundice, liver disease with impaired bilirubin excretion, testicular and hepatic carcinoma.
DOSAGE AND DIRECTIONS FOR USE:
DECABOLIN injections should be administered intramusculary, preferably deep into the gluteal muscle. When using Nandrolone decanoate injection, an adequate iron intake is required for maximum response. If any solid matters separate out, it should be redissolved by warming before use.
Adults:
Effective Dose Males – Intramuscular, 200 – 600 mg/week (2 mg/lb of Body weight)
Effective Dose Females – Intramuscular, 50 to 100 mg/week
Active life: 15 days
SIDE EFFECTS:
Oedema, cholestatic jaundice, hepatic carcinoma. Gynaecomastia. Precocious puberty & shortening of stature due to early closure of epiphysis. Rashes, cramps, dyspepsia. Virilisation which appears in sensitive women as hoarseness, acne, hirsutism, and increased libido and menstrual irregularities.
PRECAUTIONS:
Patients with the following conditions should be monitored:
1) In cardiac failure, renal dysfunction, hypertension, epilepsy or migraine (or a history of these conditions), since anabolic steroids may induce salt and fluid retention.
2) Diabetes, since anabolic steroids may improve the glucose tolerance and decrease the need for insulin or other antidiabetic drugs.
3) Incomplete statural growth, since anabolic steroids in high dosages may accelerate epiphyseal closure.
4) Skeletal metastases, since anabolic steroids may induce hypercalcemia and hypercalciuria in these patients.
5) Liver dysfunction.
6) If signs of virilization develops, treatment should be discontinued.
DRUG INTERACTIONS:
Potentiates corticosteroids. Potentiates oral anticoagulants, thereby enhancing bleeding tendency. Liver-enzyme-inducing agents may reduce the effects of DECABOLIN by enhancing its metabolism in the liver. Reducing efficacy of cyclophosphamide in advanced breast cancer.
OVERDOSAGE:
Acute intramuscular toxicity of Nandrolone is very low.
STORAGE CONDITIONS:
Store in a cool dry place below 25 °C.
Not to be refrigerated.
Protect from light.
Keep out of reach of children.
PACKAGING: BOX:
5 vials of 2 ml (250 mg/ml)
MARKETED BY:
Pharmed Corporation Ltd., 3361/A, Rani Bagh, Mahindra Park Rajdhani Enclave, Shakurpur, New Delhi, Delhi 110034, India tel +919953242466, http://www.pharmed-corp.com
DATE OF PUBLICATION OF THIS PACKAGE INSERT:
04.2020
